Anti-Mortalin/GRP75 Antibody FL550 Conjugate (N52A/42)

Name: Anti-Mortalin/GRP75 Antibody FL550 Conjugate
Brand: NeuroMab
SKU: 75-127-FL550
Price: 515.0 USD
Availability: InStock

Our Anti-Mortalin/GRP75 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N52A/42. It detects human, mouse, and rat Mortalin/GRP75, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Human, Mouse, Non-Human Primate, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

490

594

650

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Data Sheet

SKU: 75-127-FL550

Volume: 200 µL

Variant

Price:

$515.00

Quantity:

Product Details

Target

Mortalin/GRP75

Target Description

Mitochondrial stress-70 protein or Mortalin/GRP75 is encoded by the gene HSPA9. Mortalin is a chaperone protein and plays a role in cell proliferation, stress response and mitochondria maintenance. It is widely expressed in tissues in mitochondria, endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. Diseases associated with this gene include Even-Plus Syndrome and Sideroblastic Anemia 4.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N52A/42

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Hspa9 Grp75 Hsp74 Hspa9a

Molecular Weight

75 kDa

Antigen

Identified as off-target mAb in screen for anti-Salm2 NeuroMabs (immunogen was fusion protein amino acids 551-766 of mouse SALM2). Target identified as Mortalin/Grp75 by LC-MS/MS analysis of protein immunopurified from rat brain using N52A/42.

Species Reactivity

Human, Mouse, Non-Human Primate, Rat

Antibody Registry ID

AB_2939473

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Mortalin) (Peptide-binding protein 74) (PBP74) (p66 MOT)

UniProt Details

UniProt (Human): P38646
UniProt (Immunogen Species): P38647

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Anti-Mortalin/GRP75 Antibody FL550 Conjugate (N52A/42)

SKU: 75-127-FL550

Product Details

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