Anti-Kv1.2 K+ Channel Antibody Biotin Conjugate (K14/16)

Name: Anti-Kv1.2 K+ Channel Antibody Biotin Conjugate
Brand: NeuroMab
SKU: 75-008-BTN
Price: 543.0 USD
Availability: InStock

Our mouse Kv1.2 K+ channel biotin conjugate monoclonal antibody from NeuroMab is produced in-house from clone K14/16. It detects gerbil, human, mouse, non-human primate, rat, Xenopus, and zebrafish Kv1.2 K+ channel and is purified by Protein A chromatography. KO validated. Works in ELISA, IHC, ICC, WB, IP.

Anti-Kv1.2 K+ Channel Antibody Biotin Conjugate

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Species Reactivity

Gerbil, Human, Mouse, Non-Human Primate, Rat, Xenopus, Zebrafish

Applications

ELISA, ICC, IHC, IP, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Carrier-Free

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Data Sheet

KO Validated

Trial Size

SKU: 75-008-BTN

Volume: 200 µL

Variant

Price:

$543.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Kv1.2 K+ channel

Scientific Background

Kv1.2 K+ channel (Potassium voltage-gated channel subfamily A member 2), which is encoded by KCNA2 gene, is part of the Potassium voltage-gated channel family. Kv1.2 K+ channel switches between its open and closed conformation in response to the voltage difference across the membrane, which selectively allows the traffic of K+. Kv1.2 K+ channel determines potassium ion permeability of excitable membranes according to their electrochemical gradient. Therefore, this protein has for function to regulate neurotransmitter release, neuronal excitability, smooth muscle contraction, heart muscle contraction or insulin secretion. Kv1.2 is recognized as a tansmembrane/ multi-pass membrane protein. Anti-Kv1.2 K+ channel K14/16 is often used in IHC on human normal cerebral cortex.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

K14/16

Isotype

IgG2b

Applications

ELISA, ICC, IHC, IP, WB

Host Species

Mouse

Gene Name

KCNA2

Molecular Weight

80 kDa

Immunogen

Fusion Protein Amino acids 428-499 (cytoplasmic C-terminus) of human Kv1.2 (accession number P63142) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Gerbil, Human, Mouse, Non-Human Primate, Rat, Xenopus, Zebrafish

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

Biotin

Specificity

No cross-reactivity against Kv1.1, Kv1.3, Kv1.4, Kv1.5 and Kv1.6 expressed in transfected cells

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Potassium voltage-gated channel subfamily A member 2 (NGK1) (Voltage-gated K(+) channel HuKIV) (Voltage-gated potassium channel HBK5) (Voltage-gated potassium channel subunit Kv1.2)

UniProt ID

P16389

Shipping

Shipped on ice packs

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Anti-Kv1.2 K+ Channel Antibody Biotin Conjugate (K14/16)

SKU: 75-008-BTN

Product Details

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