Anti-Kv1.2 K+ Channel Antibody FL550 Conjugate (K14/16)

Name: Anti-Kv1.2 K+ Channel Antibody FL550 Conjugate
Brand: NeuroMab
SKU: 75-008-FL550
Price: 499.0 USD
Availability: InStock

from NeuroMab Datasheet

KO Validated

Available Conjugates

Unconjugated

490

594

650

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

K14/16

Applications

ICC, IHC

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

KCNA2

Molecular Weight

80 kDa

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Volume: 200 µL

Variant

Price:

$499

Quantity:

Bulk Order Anti-Kv1.2 K+ Channel Antibody FL550 Conjugate

Product Details

Target

Kv1.2 K+ channel

Target Description

Kv1.2 K+ channel (Potassium voltage-gated channel subfamily A member 2), which is encoded by KCNA2 gene, is part of the Potassium voltage-gated channel family. Kv1.2 K+ channel switches between its open and closed conformation in response to the voltage difference across the membrane, which selectively allows the traffic of K+. Kv1.2 K+ channel determines potassium ion permeability of excitable membranes according to their electrochemical gradient. Therefore, this protein has for function to regulate neurotransmitter release, neuronal excitability, smooth muscle contraction, heart muscle contraction or insulin secretion. Kv1.2 is recognized as a tansmembrane/ multi-pass membrane protein. Anti-Kv1.2 K+ channel K14/16 is often used in IHC on human normal cerebral cortex.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

K14/16

Isotype

IgG2b

Applications

ICC, IHC

Host Species

Mouse

Gene Name

KCNA2

Molecular Weight

80 kDa

Antigen

Fusion protein amino acids 428-499(cytoplasmic C-terminus) of rat Kv1.2 (accession number P63142) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939093

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

No cross-reactivity against Kv1.1, Kv1.3, Kv1.4, Kv1.5 and Kv1.6 expressed in transfected cells

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Potassium voltage-gated channel subfamily A member 2 (NGK1) (Voltage-gated K(+) channel HuKIV) (Voltage-gated potassium channel HBK5) (Voltage-gated potassium channel subunit Kv1.2)

UniProt Details

UniProt (Human): P16389
UniProt (Immunogen Species): P16389

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Anti-Kv1.2 K+ Channel Antibody FL550 Conjugate (K14/16)

Available Conjugates

Anti-Kv1.2 K+ Channel Antibody FL550 Conjugate
SKU: 75-008-FL550

Bulk Order Anti-Kv1.2 K+ Channel Antibody FL550 Conjugate

Product Details

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Anti-Kv1.2 K+ Channel Antibody FL550 Conjugate (K14/16)

Available Conjugates

Anti-Kv1.2 K+ Channel Antibody FL550 Conjugate SKU: 75-008-FL550

Bulk Order Anti-Kv1.2 K+ Channel Antibody FL550 Conjugate

Product Details

Anti-Kv1.2 K+ Channel Antibody FL550 Conjugate
SKU: 75-008-FL550