Anti-Kir2.3 K+ Channel Antibody FL594 Conjugate (N25/35)

Name: Anti-Kir2.3 K+ Channel Antibody FL594 Conjugate
Brand: NeuroMab
SKU: 75-069-FL594
Price: 486.0 USD
Availability: InStock

Our mouse Kir2.3 K+ channel FL594 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N25/35. It detects human, mouse, and rat Kir2.3 K+ channel and is purified by Protein A chromatography. Works in IHC, ICC.

Anti-Kir2.3 K+ Channel Antibody FL594 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-069-FL594

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Kir2.3 K+ channel

Scientific Background

Inward rectifier potassium channel 4 or Kir2.3 is encoded by the gene KCNJ4. Kir2.3 is a member of the inward rectifier potassium ion channel family and plays a role in excitability of muscle cells and neurons. Kir2.3 is an integral membrane protein that is found expressed in heart, skeletal muscle, and several different brain regions including the hippocampus. Diseases associated with KCNJ4 include Long Qt Syndrome 9 and Seizures, Sensorineural Deafness, Ataxia, Mental Retardation, And Electrolyte Imbalance.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N25/35

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

KCNJ4 IRK3

Molecular Weight

45 kDa

Immunogen

Fusion protein amino acids 390-445 of human Kir2.3 (accession number NP_032453) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939286

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL594 Ex: 594 nm, Em: 615 nm

Specificity

No cross-reactivity against Kir2.1 or Kir2.2

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Inward rectifier potassium channel 4 (HIRK2) (HRK1) (Hippocampal inward rectifier) (HIR) (Inward rectifier K(+) channel Kir2.3) (IRK-3) (Potassium channel, inwardly rectifying subfamily J member 4)

UniProt ID

P48050

Shipping

Shipped on ice packs

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Anti-Kir2.3 K+ Channel Antibody FL594 Conjugate (N25/35)

SKU: 75-069-FL594

Product Details

Bulk Order Anti-Kir2.3 K+ Channel Antibody FL594 Conjugate

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