Anti-Kir2.3 K+ Channel Antibody FL490 Conjugate (N25/35)
Our Anti-Kir2.3 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N25/35. It detects human, mouse, and rat Kir2.3 K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
SKU: 75-069-FL490
Product Details
Kir2.3 K+ channel
Inward rectifier potassium channel 4 or Kir2.3 is encoded by the gene KCNJ4. Kir2.3 is a member of the inward rectifier potassium ion channel family and plays a role in excitability of muscle cells and neurons. Kir2.3 is an integral membrane protein that is found expressed in heart, skeletal muscle, and several different brain regions including the hippocampus. Diseases associated with KCNJ4 include Long Qt Syndrome 9 and Seizures, Sensorineural Deafness, Ataxia, Mental Retardation, And Electrolyte Imbalance.
Purified by Protein A chromatography
0.5 mg/mL
Monoclonal
N25/35
IgG1
ICC, IHC
Mouse
KCNJ4 IRK3
45 kDa
Fusion protein amino acids 390-445 of human Kir2.3 (accession number NP_032453) produced recombinantly in E. Coli
Human, Mouse, Rat
AB_2939284
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL490 Ex: 491 nm, Em: 515 nm
No cross-reactivity against Kir2.1 or Kir2.2
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
12 months from date of receipt
Shipped on ice packs
Inward rectifier potassium channel 4 (HIRK2) (HRK1) (Hippocampal inward rectifier) (HIR) (Inward rectifier K(+) channel Kir2.3) (IRK-3) (Potassium channel, inwardly rectifying subfamily J member 4)
UniProt (Human): P48050
UniProt (Immunogen Species): P48050
UniProt (Immunogen Species): P48050