Inward rectifier potassium channel 4 or Kir2.3 is encoded by the gene KCNJ4. Kir2.3 is a member of the inward rectifier potassium ion channel family and plays a role in excitability of muscle cells and neurons. Kir2.3 is an integral membrane protein that is found expressed in heart, skeletal muscle, and several different brain regions including the hippocampus. Diseases associated with KCNJ4 include Long Qt Syndrome 9 and Seizures, Sensorineural Deafness, Ataxia, Mental Retardation, And Electrolyte Imbalance.
Fusion protein amino acids 390-445 of human Kir2.3 (accession number NP_032453); Mouse: 96% identity (55/57 amino acids identical); Rat: 94% identity (54/57 amino acids identical)
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
No cross-reactivity against Kir2.1 or Kir2.2
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.