Anti-GluN2C/NR2C Antibody (BSA and Azide free) (N422/18)

Name: Anti-GluN2C/NR2C Antibody (BSA and Azide free)
Brand: NeuroMab
SKU: 75-411-CF
Price: 486.0 USD
Availability: InStock

Our mouse GluN2C/NR2C carrier-free monoclonal antibody from NeuroMab is produced in-house from clone N422/18. It detects human, mouse, and rat GluN2C/NR2C and is purified by Protein A chromatography. KO validated. Works in WB, IHC, ICC, ELISA.

Anti-GluN2C/NR2C Antibody (BSA and Azide free)

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Biotin

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Data Sheet

KO Validated

SKU: 75-411-CF

Volume: 100 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

GluN2C/NR2C

Scientific Background

Glutamate receptor ionotropic, NMDA 2C, Nmethyl D-aspartate receptor subtype 2C, or GluN2C/NR2C is encoded by the gene GRIN2C. GluN2C is a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of channel forming ionotropic glutamate receptor which is permeable to cations including calcium, potassium and sodium. GluN2C is found in the central nervous system and the cerebellum. GluN2C is thought to have an important role in physiological processes such as learning, memory, and synaptic development. Diseases associated with this gene include Alzheimer disease, Parkinson’s disease and Schizophrenia.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.6-1.0 mg/mL

Clonality

Monoclonal

Clone

N422/18

Isotype

IgG1

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

Grin2c

Molecular Weight

130 kDa

Immunogen

Fusion protein amino acids 836-1233 (cytoplasmic C-terminus) of rat GluN2C (accession number Q00961) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Human, Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Buffer

PBS

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Glutamate receptor ionotropic, NMDA 2C (GluN2C) (Glutamate [NMDA] receptor subunit epsilon-3) (N-methyl D-aspartate receptor subtype 2C) (NMDAR2C) (NR2C)

UniProt ID

Q00961

Shipping

Shipped on ice packs

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Anti-GluN2C/NR2C Antibody (BSA and Azide free) (N422/18)

SKU: 75-411-CF

Product Details

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