Anti-GluN2C/NR2C Antibody FL650 Conjugate (N422/18)

Name: Anti-GluN2C/NR2C Antibody FL650 Conjugate
Brand: NeuroMab
SKU: 75-411-FL650
Price: 445.0 USD
Availability: InStock

from NeuroMab Datasheet

KO Validated

Available Conjugates

Unconjugated

490

550

594

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

N422/18

Applications

ICC, IHC

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

Grin2c

Molecular Weight

130 kDa

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Volume: 200 µL

Variant

Price:

$445

Quantity:

Bulk Order Anti-GluN2C/NR2C Antibody FL650 Conjugate

Product Details

Target

GluN2C/NR2C

Target Description

Glutamate receptor ionotropic, NMDA 2C, Nmethyl D-aspartate receptor subtype 2C, or GluN2C/NR2C is encoded by the gene GRIN2C. GluN2C is a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of channel forming ionotropic glutamate receptor which is permeable to cations including calcium, potassium and sodium. GluN2C is found in the central nervous system and the cerebellum. GluN2C is thought to have an important role in physiological processes such as learning, memory, and synaptic development. Diseases associated with this gene include Alzheimer disease, Parkinson’s disease and Schizophrenia.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N422/18

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Grin2c

Molecular Weight

130 kDa

Antigen

Fusion protein amino acids 836-1233 (cytoplasmic C-terminus) of rat GluN2C (accession number Q00961) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2940363

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Glutamate receptor ionotropic, NMDA 2C (GluN2C) (Glutamate [NMDA] receptor subunit epsilon-3) (N-methyl D-aspartate receptor subtype 2C) (NMDAR2C) (NR2C)

UniProt Details

UniProt (Human): Q14957
UniProt (Immunogen Species): Q00961

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Anti-GluN2C/NR2C Antibody FL650 Conjugate (N422/18)

Available Conjugates

Anti-GluN2C/NR2C Antibody FL650 Conjugate
SKU: 75-411-FL650

Bulk Order Anti-GluN2C/NR2C Antibody FL650 Conjugate

Product Details

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Anti-GluN2C/NR2C Antibody FL650 Conjugate (N422/18)

Available Conjugates

Anti-GluN2C/NR2C Antibody FL650 Conjugate SKU: 75-411-FL650

Bulk Order Anti-GluN2C/NR2C Antibody FL650 Conjugate

Product Details

Anti-GluN2C/NR2C Antibody FL650 Conjugate
SKU: 75-411-FL650