Human Mouse Rat
IHC IP WB
Synthetic peptide amino acids 477-498 of human Wave1/Wasp family 1(CQVIPASEPKRHPSTLPVISDAR; accession number Q92558)
Rat: 95% identity (21/22)
Mouse=95% identity (21/22)
Wiskott-Aldrich syndrome protein family member 1 (WASP family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1)
WASF1 KIAA0269 SCAR1 WAVE1
TC Supernatant: AB_10671317
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody has been knockout-validated in mouse brain (by Western blot and/or immunohistochemistry).
This antibody recognizes a single immunoreactive band of expected molecularweight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
Citations and References
- Hsiao K, Harony-Nicolas H, Buxbaum JD, Bozdagi-Gunal O, Benson DL.. (2016), 'Cyfip1 Regulates Presynaptic Activity during Development. .' Journal of Neuroscience. 10.1523/JNEUROSCI.0511-15.2016. " "
- Chazeau A, Mehidi A, Nair D, Gautier JJ, Leduc C, Chamma I, Kage F, Kechkar A, Thoumine O, Rottner K, Choquet D, Gautreau A, Sibarita JB, Giannone G.. (2014), 'Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion. .' The EMBO Journal. 10.15252/embj.201488837. " "
- Chia PH, Chen B, Li P, Rosen MK, Shen K.. (), 'Local F-actin network links synapse formation and axon branching. .' Cell. 10.1016/j.cell.2013.12.009. " "
- Chen B, Brinkmann K, Chen Z, Pak CW, Liao Y, Shi S, Henry L, Grishin NV, Bogdan S, Rosen MK.. (), 'The WAVE regulatory complex links diverse receptors to the actin cytoskeleton. .' Cell. 10.1016/j.cell.2013.11.048. " "
- Han K, Holder JL Jr, Schaaf CP, Lu H, Chen H, Kang H, Tang J, Wu Z, Hao S, Cheung SW, Yu P, Sun H, Breman AM, Patel A, Lu HC, Zoghbi HY.. (2013), 'SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties. .' Nature. 10.1038/nature12630. " "
- Khodosevich K, Seeburg PH, Monyer H.. (2009), 'Major signaling pathways in migrating neuroblasts. .' Frontiers in Molecular Neuroscience. 10.3389/neuro.02.007.2009. " "
- Cheng A, Arumugam TV, Liu D, Khatri RG, Mustafa K, Kwak S, Ling HP, Gonzales C, Xin O, Jo DG, Guo Z, Mark RJ, Mattson MP.. (2007), 'Pancortin-2 interacts with WAVE1 and Bcl-xL in a mitochondria-associated protein complex that mediates ischemic neuronal death. .' Journal of Neuroscience. 10.1523/JNEUROSCI.5154-06.2007. "