Our Anti-WAVE1/SCAR mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K91/36. It is KO validated, detects human, mouse, and rat WAVE1/SCAR, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
Wiskott-Aldrich syndrome protein family member 1, Verprolin Homology Domain-Containing Protein 1, Protein WAVE-1 or SCAR1 is encoded by the gene WASF1 and is a member of the Wiskott-Aldrich syndrome protein (WASP)-family. WAVE1/SCAR is an effector protein which transmits of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. WAVE1/SCAR acts as part of the WAVE complex which is involved in the regulation of actin filament reorganization and membrane ruffling. WAVE1/SCAR is expressed in many tissues including brain, ovary, colon, kidney, pancreas and thymus. Diseases associated with this gene include Wiskott-Aldrich Syndrome and Alacrima, Achalasia, And Mental Retardation Syndrome.
Purified by Protein A chromatography
WASF1 KIAA0269 SCAR1 WAVE1
Synthetic peptide amino acids 477-498 of human Wave1/Wasp family 1(CQVIPASEPKRHPSTLPVISDAR; accession number Q92558)
Human, Mouse, Rat
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL550 Ex: 550 nm, Em: 575 nm
No cross-reactivity reported
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
12 months from date of receipt
Shipped on ice packs
Wiskott-Aldrich syndrome protein family member 1 (WASP family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1)