Products: Primary Antibodies

Anti-TrpV3 Antibody (N15/39)

from NeuroMab

PRODUCT OPTIONS

Brand	Catalog #	Option	Volume	Concentration	Price
Brand	Catalog # 75-070	Option Purified	Volume 100 µL	Concentration 1 mg/mL	Price $275.00
Brand	Catalog # 73-070	Option TC Supernatant	Volume 5 mL	Concentration Lot dependent	Price $275.00

"TC Supernatant" vs. "Purified"

TC Supernatant
Hybridoma tissue-culture supernatant (5mL) generally containing 10-50 ug/mL monoclonal antibody (clone-dependent) can be a very economical choice. Supernatant is suitable for most applications including Western Blot, immunocytochemistry, immunohistochemistry etc. For applications requiring higher antibody concentration or purity (such as immunoprecipitation, microinjection, or conjugation) it is recommended that you purchase the purified form of the antibody (supplied at 1mg/mL).

Purified mAbs
Produced by in vitro bioreactor culture of hybridoma lines followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody at 1mg/mL.

Validation Images

Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG1

Species Reactivity:

Human Mouse Rat

Applications:

ICC IP WB

Target Description:

Transient receptor potential cation channel subfamily V member 3 or TrpV3 is encoded by the gene TprV3. TrpV3 is a member of the transient receptor potential cation channel family. TrpV3 is thought to function in a variety of processes, including temperature sensation and vasoregulation. This channel is activated at temperatures between 22 and 40 °C. TrpV3 is found at the membrane in the CNS, PNS and skin where it acts as a transducer of thermal stimuli. Diseases associated with TRPV3 include several types of Keratoderma.

Immunogen:

Synthetic peptide amino acids 774-791 (C-terminus) of rat TrpV3(KTTLYAFDELDEFPETSV; E9PU0028); Human: 77% identity (14/18 amino acids identical); Mouse: 100% identity (18/18 amino acids identical); Common to all TrpV3 splice variants

Cross Reactivity:

No cross-reactivity reported

Protein Name(s):

TrpV3

Gene Name(s):

TrpV3

Antibody Registry ID:

Purified: AB_10698038
TC Supernatant: AB_10675456

Antibody Validation and Application Notes

This antibody has been validated using the following assays:

Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Molecular Weight:

70 kDa

Quality Control

The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.