Transient receptor potential cation channel subfamily V member 3 or TrpV3 is encoded by the gene TprV3. TrpV3 is a member of the transient receptor potential cation channel family. TrpV3 is thought to function in a variety of processes, including temperature sensation and vasoregulation. This channel is activated at temperatures between 22 and 40 °C. TrpV3 is found at the membrane in the CNS, PNS and skin where it acts as a transducer of thermal stimuli. Diseases associated with TRPV3 include several types of Keratoderma.
Purified by Protein A chromatography
Synthetic peptide amino acids 774-791 (C-terminus) of rat TrpV3 (KTTLYAFDELDEFPETSV; accession number E9PU00)
Human, Mouse, Rat
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL550 Ex: 550 nm, Em: 575 nm
No cross-reactivity reported
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
12 months from date of receipt
Shipped on ice packs
Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3)