Fusion protein amino acids 20-216 (extracellular N-terminus, EGF-like domains 1-5) of mouse Notch1 (also known as Neurogenic locus notch homolog protein 1, hN1, Translocationassociated notch protein, TAN-1, Motch A, mT14, p300 and Motch, accession number Q01705) Rat: 93% identity (185/197 amino acids identical) Human: 84% identity (166/197 amino acids identical) ~40% identity with Notch2, Notch3 and Notch4
Does not cross-react with Notch2 or Notch3
Neurogenic locus notch homolog protein 1 (Notch 1) (Motch A) (mT14) (p300) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
TC Supernatant: AB_2315897
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecularweight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
>270 kDa, ~120 kDa and smaller fragments (due to proteolysis)
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.