Anti-Notch1 Antibody FL490 Conjugate (N253/32)

Name: Anti-Notch1 Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-295-FL490
Price: 474.0 USD
Availability: InStock

Our Anti-Notch1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N253/32. It detects mouse and rat Notch1, and is purified by Protein A chromatography. It is great for use in ICC.

Species Reactivity

Mouse, Rat

Applications

ICC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Carrier-Free

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Data Sheet

SKU: 75-295-FL490

Volume: 200 µL

Variant

Price:

$474.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Notch1

Target Description

Notch Receptor 1 is encoded by the gene NOTCH1. NOTCH1 is a member of the NOTCH family. NOTCH1 is involved in processes related to cell fate specification, differentiation, proliferation, and survival. NOTCH1 is highly expressed in the brain, lungs, and thymus. Diseases associated with NOTCH1 include Aortic Valve Disease 1 and Adams-Oliver Syndrome 5.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N253/32

Isotype

IgG1

Applications

ICC

Host Species

Mouse

Gene Name

Notch1 Motch

Molecular Weight

>270 kDa, ~120 kDa and smaller fragments (due to proteolysis)

Antigen

Fusion protein amino acids 20-216 (extracellular N-terminus, EGF-like domains 1-5) of mouse Notch1 (accession number Q01705) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2940036

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not cross-react with Notch2 or Notch3

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Neurogenic locus notch homolog protein 1 (Notch 1) (Motch A) (mT14) (p300) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]

UniProt ID

Q01705

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Anti-Notch1 Antibody FL490 Conjugate (N253/32)

SKU: 75-295-FL490

Product Details

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