Human Mouse Rat
ICC IHC WB
Synthetic peptide amino acids 475-489 (MSNMSDQGPYNEYEP, cytoplasmic C-terminus) of human LRRTM2 (also known as Leucine-rich repeat transmembrane neuronal protein 2, Leucinerich repeat neuronal 2 protein, LRRN2 and KIAA0416, accession number O43300) Mouse: 100% identity (15/15 amino acids identical) Rat: 93% identity (14/15 amino acids identical) <50% identity with LRRTM1, LRRTM3 and LRRTM4
Does not cross-react with LRRTM1
Leucine-rich repeat transmembrane neuronal protein 2 (Leucine-rich repeat neuronal 2 protein)
LRRTM2 KIAA0416 LRRN2
TC Supernatant: AB_2315885
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody has been knockout-validated in mouse brain (by Western blot and/or immunohistochemistry).
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.
This antibody recognizes a single immunoreactive band of expected molecularweight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
80 kDa (and larger due to glycosylation)
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
Citations and References
- Calafate S1, Buist A2, Miskiewicz K3, Vijayan V3, Daneels G2, de Strooper B3, de Wit J3, Verstreken P4, Moechars D5.. (2015), 'Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation..' Cell Rep. . 10.1016/j.celrep.2015.04.043.