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Products: Primary Antibodies

Anti-LRRK1 (N341/12)


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PRODUCT OPTIONS

Catalog # Option Volume Concentration Price*
Catalog #
75-347
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$269.00
Catalog #
73-347
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$269.00

Validation Images


Overview

Brand:

NeuroMab

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG1

Species Reactivity:

Human Mouse

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

ICC WB

Immunogen:

Fusion protein amino acids 1695-2015 (C-terminus) of human LRRK1 (also known as Leucine-rich repeat serine/threonine-protein kinase 1 and KIAA1790, accession number Q38SD2) Mouse: 81% identity (263/321 amino acids identical) Rat: 79% identity (254/321 amino acids identical) <50% identity with LRRK2 This NeuroMab antibody is considered "Restricted" and is therefore not available for commercial re-distribution on a for-profit basis.

Cross Reactivity:

Does not cross-react with LRRK2

Protein Name(s):

Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1)

Gene Name(s):

LRRK1 KIAA1790

Antibody Registry ID:

Purified: AB_2315880
TC Supernatant: AB_2315879


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Knockout Validation:

This antibody has been knockout-validated in mouse brain (by Western blot and/or immunohistochemistry).

Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.

This antibody recognizes a single immunoreactive band of expected molecularweight when used to probe brain lysate.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Molecular Weight:

>200 kDa


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.