Human Mouse Rat
IHC IP WB
Synthetic peptide amino acids 9-28 (ADIPSPKLGLPKSSESALKC, unique Nterminus) of human Kv1.2 (accession number NP_003462)
Rat: 100% identity (20/20 amino acids identical)
Voltage-gated potassium channel subunit beta-1 (EC 1.1.1.-) (K(+) channel subunit beta-1) (Kv-beta-1)
TC Supernatant: AB_10671827
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody has been knockout-validated in mouse brain (by Western blot and/or immunohistochemistry).
This antibody recognizes a single immunoreactive band of expected molecularweight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
Citations and References
- Hund TJ, Snyder JS, Wu X, Glynn P, Koval OM, Onal B, Leymaster ND, Unudurthi SD, Curran J, Camardo C, Wright PJ, Binkley PF, Anderson ME, Mohler PJ.. (2014), 'β(IV)-Spectrin regulates TREK-1 membrane targeting in the heart. .' Cardiovascular Research. 10.1093/cvr/cvu008. " "
- Ovsepian SV, Steuber V, Le Berre M, O'Hara L, O'Leary VB, Dolly JO.. (2013), 'A defined heteromeric KV1 channel stabilizes the intrinsic pacemaking and regulates the output of deep cerebellar nuclear neurons to thalamic targets. .' The Journal of Physiology. 10.1113/jphysiol.2012.249706. " "
- Tipparaju SM, Li XP, Kilfoil PJ, Xue B, Uversky VN, Bhatnagar A, Barski OA.. (2012), 'Interactions between the C-terminus of Kv1.5 and Kvβ regulate pyridine nucleotide-dependent changes in channel gating. .' Pflügers Archiv: European Journal of Physiology. 10.1007/s00424-012-1093-z. "