Anti-Kvbeta1.2 K+ Channel Antibody FL594 Conjugate (K47/42)

Name: Anti-Kvbeta1.2 K+ Channel Antibody FL594 Conjugate
Brand: NeuroMab
SKU: 75-019-FL594
Price: 445.0 USD
Availability: InStock

from NeuroMab Datasheet

KO Validated

Available Conjugates

Unconjugated

490

550

650

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

K47/42

Applications

ICC, IHC

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

KCNAB1 KCNA1B

Molecular Weight

65 kDa

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Volume: 200 µL

Variant

Price:

$445

Quantity:

Bulk Order Anti-Kvbeta1.2 K+ Channel Antibody FL594 Conjugate

Product Details

Target

Kvbeta1.2 K+ channel

Target Description

Voltage-gated potassium channel subunit beta-1 or Kvβ1.1 is encoded by the gene KCNAB1. Kvß1.1 is a member of the potassium channel, voltage-gated, shaker-related subfamily. Alternative splicing of KCNAB1 allows for three distinct proteins to be made, Kvß1.1, Kvß1.2, and Kvß1.3. Each of these has a unique N terminus. Kvβ1.1 is a cytoplasmic subunit that modulates the characteristics of the membrane spanning, channel-forming alpha-subunits. Beta subunits can promote the closure of channels or enhance channel activity depending on the channel members. Kvß1 is predominantly expressed in brain and found in hippocampus, cerebral cortex, caudate putamen, colliculus and cerebellum. Diseases associated with this gene include Episodic Ataxia, Type 1 and Familial Temporal Lobe Epilepsy, 3

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

K47/42

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

KCNAB1 KCNA1B

Molecular Weight

65 kDa

Antigen

Synthetic peptide amino acids 9-28 (ADIPSPKLGLPKSSESALKC, unique Nterminus) of human Kv1.2 (accession number NP_003462)

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939138

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL594 Ex: 594 nm, Em: 615 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Voltage-gated potassium channel subunit beta-1 (EC 1.1.1.-) (K(+) channel subunit beta-1) (Kv-beta-1)

UniProt Details

UniProt (Human): Q14722
UniProt (Immunogen Species): Q14722-3

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Anti-Kvbeta1.2 K+ Channel Antibody FL594 Conjugate (K47/42)

Available Conjugates

Anti-Kvbeta1.2 K+ Channel Antibody FL594 Conjugate
SKU: 75-019-FL594

Bulk Order Anti-Kvbeta1.2 K+ Channel Antibody FL594 Conjugate

Product Details

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Anti-Kvbeta1.2 K+ Channel Antibody FL594 Conjugate (K47/42)

Available Conjugates

Anti-Kvbeta1.2 K+ Channel Antibody FL594 Conjugate SKU: 75-019-FL594

Bulk Order Anti-Kvbeta1.2 K+ Channel Antibody FL594 Conjugate

Product Details

Anti-Kvbeta1.2 K+ Channel Antibody FL594 Conjugate
SKU: 75-019-FL594