Products: Primary Antibodies

Anti-Histone H2A.Z acetyl-Lys4/7/11 Antibody (N299/39)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
75-319
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00
Brand
NeuroMab Logo
Catalog #
73-319
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG1

Species Reactivity:

Human Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

DB ELISA

Target Description:

H2A.Z Variant Histone 1 is encoded by the gene H2AZ1. H2AZ1 is a member of the histone H2A family. H2AZ1 is a variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic fatality. H2AZ1 is expressed in 239 organs with the highest levels in the myometrium. Diseases associated with H2AZ1 include testicular spermatocytic seminoma.

Immunogen:

Synthetic peptide amino acids 2-15 (AGG[acetyl-K]AG[acetyl-K]DSG[acetyl-K]AKT) of human Histone H2A.Z (also known as Histone H2A/Z, accession number P0C0S5)
Mouse: 100% identity (14/14 amino acids identical)
Human: 100% identity (14/14 amino acids identical)
93% identity with Histone H2A.V

Cross Reactivity:

Does not cross-react with unacetylated Histone H2A.Z Does not cross-react with Histones H2A acetyl-Lys4/8 or H4 acetyl-Lys4/7/11/15

Protein Name(s):

Histone H2A.Z (H2A/z)

Gene Name(s):

H2AFZ H2AZ

Antibody Registry ID:

Purified: AB_2315848
TC Supernatant: AB_2315847


Antibody Validation and Application Notes


This antibody has been validated using the following assays: