Anti-Histone H2A.Z Acetyl-Lys4/7/11 Antibody (N299/39)

Name: Anti-Histone H2A.Z Acetyl-Lys4/7/11 Antibody
Brand: NeuroMab
SKU: 75-319
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

1 Citation

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

N299/39

Applications

DB, ELISA

Host Species

Mouse

Format

Purified

Gene Name

H2AFZ H2AZ

Molecular Weight

13 kDa

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Serial dilutions of BSA-conjugated modified and unmodified peptides dotted onto membrane and probed with N299/39 TC supe (left) and a mouse loading control (right).

Volume: 100 µL

Variant

Price:

$308

Quantity:

Bulk Order Anti-Histone H2A.Z Acetyl-Lys4/7/11 Antibody

Product Details

Target

Histone H2A.Z (H2A/z)

Target Description

H2A.Z Variant Histone 1 is encoded by the gene H2AZ1. H2AZ1 is a member of the histone H2A family. H2AZ1 is a variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic fatality. H2AZ1 is expressed in 239 organs with the highest levels in the myometrium. Diseases associated with H2AZ1 include testicular spermatocytic seminoma.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N299/39

Isotype

IgG1

Applications

DB, ELISA

Host Species

Mouse

Gene Name

H2AFZ H2AZ

Molecular Weight

13 kDa

Antigen

Synthetic peptide amino acids 2-15 (AGG[acetyl-K]AG[acetyl-K]DSG[acetyl-K]AKT) of human Histone H2A.Z (also known as Histone H2A/Z, accession number P0C0S5); Mouse: 100% identity (14/14 amino acids identical); Human: 100% identity (14/14 amino acids identical); 93% identity with Histone H2A.V

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2315848

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Does not cross-react with unacetylated Histone H2A.Z Does not cross-react with Histones H2A acetyl-Lys4/8 or H4 acetyl-Lys4/7/11/15

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Histone H2A.Z (H2A/z)

UniProt Details

UniProt (Human): P0C0S5
UniProt (Immunogen Species): P0C0S5

Satterlee JS, Beckel-Mitchener A, McAllister K, Procaccini DC, Rutter JL, Tyson FL, Chadwick LH. (2015), 'Community resources and technologies developed through the NIH Roadmap Epigenomics Program..' Methods Mol Biol.. 10.1007/978-1-4939-1804-1_2.

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Anti-Histone H2A.Z Acetyl-Lys4/7/11 Antibody (N299/39)

Anti-Histone H2A.Z Acetyl-Lys4/7/11 Antibody
SKU: 75-319

Bulk Order Anti-Histone H2A.Z Acetyl-Lys4/7/11 Antibody

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Anti-Histone H2A.Z Acetyl-Lys4/7/11 Antibody (N299/39)

Anti-Histone H2A.Z Acetyl-Lys4/7/11 Antibody SKU: 75-319

Bulk Order Anti-Histone H2A.Z Acetyl-Lys4/7/11 Antibody

Product Details

Anti-Histone H2A.Z Acetyl-Lys4/7/11 Antibody
SKU: 75-319