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Products: Primary Antibodies

Anti-Celf4/Brunol4 Antibody (N446/80)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
75-438
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00
Brand
NeuroMab Logo
Catalog #
73-438
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG2a

Species Reactivity:

Human Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

ICC IHC WB

Target Description:

CUGBP Elav-like family member 4 (CELF4), or Brunol4 is encoded by the gene CELF4. CELF4 is a RNA-binding protein which is involved in the regulation of pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. CELF4 is expressed ubiquitously in tissues, and strongly expressed in brain. Diseases associated with CELF4 include Speech and Communication Disorders and Specific Language Impairment.

Immunogen:

Fusion protein amino acids 2-87 (N-terminus) of human Celf4 (also known as CUGBP Elav-like family member 4, CUG-BP- and ETR-3-like factor 4, Bruno-like protein 4, RNA-binding protein BRUNOL-4 and Brul4, accession number Q9BZC1)
Mouse: 100% identity (86/86 amino acids identical)
50% identity with Celf6 and other Celf proteins

Cross Reactivity:

Does not cross-react with Celf6

Protein Name(s):

CUGBP Elav-like family member 4 (CELF-4) (Bruno-like protein 4) (CUG-BP- and ETR-3-like factor 4) (RNA-binding protein BRUNOL-4)

Gene Name(s):

CELF4 BRUNOL4

Antibody Registry ID:

Purified: AB_2714204
TC Supernatant: AB_2560961


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Immunohistochemistry:
This antibody shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.

Molecular Weight:

50 kDa


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.