Anti-VMAT1 Antibody (N440/21)
Our Anti-VMAT1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N440/21. It detects mouse and rat VMAT1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
SKU: 75-430
Product Details
VMAT1
Vesicular monamine transporters (VMATs) sequester neurotransmitters such as dopamine, serotonin and adrenaline into synaptic vesicles (Erickson et al., 1996). Two VMATs have been identified, VMAT1 and VMAT2. VMAT1 shows a higher affinity for serotonin (Brunk et al., 2006). Antibodies specific for VMATs have been used to monitor expression of the transporter during development and in aging and can be effectively used as a marker for monoamine terminals (Haycock et al., 2003; Witkovsky et al., 2005).
Purified by Protein A chromatography
1 mg/mL
Monoclonal
N440/21
IgG1
ICC, IHC, WB
Mouse
Slc18a1 Vmat1
100 kDa
Fusion protein amino acids 43-135 (first lumenal domain) of mouse Slc18a1 (accession number Q8R090) produced recombinantly in E. Coli
Mouse, Rat
AB_2631239
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Unconjugated
Does not cross-react with VMAT2
Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from date of receipt
Shipped on ice packs
Chromaffin granule amine transporter (Solute carrier family 18 member 1) (Vesicular amine transporter 1) (VAT1)
UniProt (Human): P54219
UniProt (Immunogen Species): Q8R090
UniProt (Immunogen Species): Q8R090