Anti-TWIK-2 K+ Channel Antibody FL490 Conjugate (N469/28)

Name: Anti-TWIK-2 K+ Channel Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-463-FL490
Price: 460.0 USD
Availability: InStock

Our Anti-TWIK-2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N469/28. It detects mouse TWIK-2, and is purified by Protein A chromatography. It is great for use in ICC.

Species Reactivity

Mouse

Applications

ICC

Host Species

Mouse

Available Conjugates

Unconjugated

550

594

650

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Data Sheet

SKU: 75-463-FL490

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

TWIK-2

Target Description

Potassium two pore domain channel subfamily K member 6 is encoded by the gene KCNK6. KCNK6 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK6 is considered an open rectifier, and is stimulated by arachidonic acid and inhibited by internal acidification and volatile anaesthetics. KCNK6 is expressed in platelets and testis. Diseases associated with KCNK6 include Thoracic Outlet Syndrome and Gingival Recession.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N469/28

Isotype

IgG1

Applications

ICC

Host Species

Mouse

Gene Name

Kcnk6

Molecular Weight

35 kDa

Antigen

Fusion protein amino acids 28-92 (first extracellular loop) of mouse TWIK-2 (accession number Q3TBV4) produced recombinantly in E. Coli

Species Reactivity

Mouse

Antibody Registry ID

AB_2940544

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

TWIK-2 (Potassium channel subfamily K member 6) (Inward rectifying potassium channel proteinTWIK-2) (TWIK-originated similarity sequence) (TWIK-2 two-pore-domain K+ channel)

UniProt Details

UniProt (Human): Q9Y257
UniProt (Immunogen Species): Q3TBV4

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Anti-TWIK-2 K+ Channel Antibody FL490 Conjugate (N469/28)

SKU: 75-463-FL490

Product Details

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