Anti-TWIK-2 K+ Channel Antibody (N469/28)

Name: Anti-TWIK-2 K+ Channel Antibody
Brand: NeuroMab
SKU: 75-463
Price: 329.0 USD
Availability: InStock

Our Anti-TWIK-2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N469/28. It detects mouse TWIK-2, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Immunoblot against extracts of COS cells transiently transfected with Myc/Flag-tagged TWIK-2 or untagged Kv2.1 plasmid probed with N469/28 (left) or rabbit anti-Flag (right)..

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Species Reactivity

Mouse

Applications

ICC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Carrier-Free

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Data Sheet

SKU: 75-463

Volume: 100 µL

Variant

Price:

$329.00

Quantity:

Ships: 1-2 business days

Product Details

Target

TWIK-2

Target Description

Potassium two pore domain channel subfamily K member 6 is encoded by the gene KCNK6. KCNK6 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK6 is considered an open rectifier, and is stimulated by arachidonic acid and inhibited by internal acidification and volatile anaesthetics. KCNK6 is expressed in platelets and testis. Diseases associated with KCNK6 include Thoracic Outlet Syndrome and Gingival Recession.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N469/28

Isotype

IgG1

Applications

ICC, WB

Host Species

Mouse

Gene Name

Kcnk6

Molecular Weight

35 kDa

Antigen

Fusion protein amino acids 28-92 (first extracellular loop) of mouse TWIK-2 (accession number Q3TBV4) produced recombinantly in E. Coli

Species Reactivity

Mouse

Antibody Registry ID

AB_2686915

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

TWIK-2 (Potassium channel subfamily K member 6) (Inward rectifying potassium channel proteinTWIK-2) (TWIK-originated similarity sequence) (TWIK-2 two-pore-domain K+ channel)

UniProt ID

Q3TBV4

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Anti-TWIK-2 K+ Channel Antibody (N469/28)

SKU: 75-463

Product Details

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