Transfected cell immunoblot. Extracts of COS-1 cells transiently transfected with rat TrpV3 (left lane) or rat Kv2.1 (right lane) plasmids and probed with K89/34 TC supe (left panel) or pure N15/4 (right panel).
Transient receptor potential cation channel subfamily V member 3 or TrpV3 is encoded by the gene TprV3. TrpV3 is a member of the transient receptor potential cation channel family. TrpV3 is thought to function in a variety of processes, including temperature sensation and vasoregulation. This channel is activated at temperatures between 22 and 40 °C. TrpV3 is found at the membrane in the CNS, PNS and skin where it acts as a transducer of thermal stimuli. Diseases associated with TRPV3 include several types of Keratoderma.
ICC, IP, WB
Synthetic peptide amino acids 774-791 (C-terminus) of rat TrpV3(KTTLYAFDELDEFPETSV; E9PU0028); Human: 77% identity (14/18 amino acids identical); Mouse: 100% identity (18/18 amino acids identical); Common to all TrpV3 splice variants
Human, Mouse, Rat
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