Anti-TRIP8b (Exon 4) Antibody FL490 Conjugate (N212/3)

Name: Anti-TRIP8b (Exon 4) Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-208-FL490
Price: 445.0 USD
Availability: InStock

from NeuroMab Datasheet

KO Validated

Available Conjugates

Unconjugated

550

594

650

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

N212/3

Applications

ICC, IHC

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

Pex5l Pex2 Pex5r Trip8b

Molecular Weight

70 kDa

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Volume: 200 µL

Variant

Price:

$445

Quantity:

Bulk Order Anti-TRIP8b (Exon 4) Antibody FL490 Conjugate

Product Details

Target

TRIP8b (exon 4)

Target Description

PEX5-related protein, Peroxisomal Biogenesis Factor 5 Like, TPR-containing Rab8b-interacting protein or TRIP8b is encoded by the gene Pex5l. It is a member of the peroxisomal targeting signal receptor family. TRIP8b is a cytoplasmic accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. TRIP8b interacts with the carboxyl-terminal region of HCN channels and regulates their cell-surface expression to the dendrites in many types of neurons. TRIP8b plays a role in regulation of HCN channel cyclic nucleotide kinetics. TRIP8b is expressed in the brain. Diseases associated with PEX5L include Rhizomelic Chondrodysplasia Punctata, Type 5 and Rhizomelic Chondrodysplasia Punctata, Type 2.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N212/3

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Pex5l Pex2 Pex5r Trip8b

Molecular Weight

70 kDa

Antigen

Fusion protein amino acids 1-192 (exon 1a, exon 4 and constant region) of rat TRIP8b (accession number Q925N3) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939772

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Specific for exon 4(does not react with TRIP8b isoforms containing exons 1a, 1b or 2)

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

PEX5-related protein (PEX5-like protein) (Peroxin-5-related protein) (TPR-containing Rab8b-interacting protein) (Tetratricopeptide repeat-containing Rab8b-interacting protein) (Pex5Rp) (TRIP8b)

UniProt Details

UniProt (Human): Q8IYB4
UniProt (Immunogen Species): Q925N3

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Anti-TRIP8b (Exon 4) Antibody FL490 Conjugate (N212/3)

Available Conjugates

Anti-TRIP8b (Exon 4) Antibody FL490 Conjugate
SKU: 75-208-FL490

Bulk Order Anti-TRIP8b (Exon 4) Antibody FL490 Conjugate

Product Details

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Anti-TRIP8b (Exon 4) Antibody FL490 Conjugate (N212/3)

Available Conjugates

Anti-TRIP8b (Exon 4) Antibody FL490 Conjugate SKU: 75-208-FL490

Bulk Order Anti-TRIP8b (Exon 4) Antibody FL490 Conjugate

Product Details

Anti-TRIP8b (Exon 4) Antibody FL490 Conjugate
SKU: 75-208-FL490