Thioredoxin 1 is encoded by the gene TRX. Thioredoxin is involved in many redox reactions in the cell and serves to reduce oxidized cysteine residues and cleave disulfide bonds. Diseases associated with TXN include Post-Cardiac Arrest Syndrome and Breast Mucinous Carcinoma.
trxA fipA tsnC b3781 JW5856
Identified as off-target monoclonal antibody in screen for anti-Stargazin NeuroMabs (immunogen was fusion protein amino acids 203-323, cytoplasmic C-terminus, of rat TARPGamma2).Target identified as Thioredoxin by ELISA and immunoblot against other Thioredoxin fusion proteins.
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.