Anti-Thioredoxin Antibody (N245/44)

Name: Anti-Thioredoxin Antibody
Brand: NeuroMab
SKU: 75-258
Price: 329.0 USD
Availability: InStock

Our Anti-Thioredoxin mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N245/44. It detects Thioredoxin, and is purified by Protein A chromatography. It is great for use in ELISA, WB.

Immunoblot against bacterially expressed Thioredoxin (TRX) and/or 6xHistidine (His) tagged fusion proteins.

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Applications

ELISA, WB

Host Species

Mouse

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Data Sheet

SKU: 75-258

Volume: 100 µL

Variant

Price:

$329.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Thioredoxin

Scientific Background

Thioredoxin 1 is encoded by the gene TRX. Thioredoxin is involved in many redox reactions in the cell and serves to reduce oxidized cysteine residues and cleave disulfide bonds. Diseases associated with TXN include Post-Cardiac Arrest Syndrome and Breast Mucinous Carcinoma.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N245/44

Isotype

IgG1

Applications

ELISA, WB

Host Species

Mouse

Gene Name

trxA fipA tsnC b3781 JW5856

Molecular Weight

12 kDa

Immunogen

Identified as off-target monoclonal antibody in screen for anti-Stargazin NeuroMabs (immunogen was fusion protein amino acids 203-323, cytoplasmic C-terminus, of rat TARPGamma2).Target identified as Thioredoxin by ELISA and immunoblot against other Thioredoxin fusion proteins.

Immunogen Species

Rat

Antibody Registry ID

AB_10676104

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Thioredoxin 1 (Trx-1)

UniProt ID

P0AA25

Shipping

Shipped on ice packs

Product Specific References for Applications and Species

Western Blot: Mouse

Western Blot: Mouse
PMID	Dilution	Publication
27667007	not listed	Park, J., et al. 2016. CaMKII phosphorylation of TARPγ-8 is a mediator of LTP and learning and memory. Neuron, 92(1), pp.75-83.. Neuron, 75-83.

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Anti-Thioredoxin Antibody (N245/44)

SKU: 75-258

Product Details

Product Specific References for Applications and Species

Bulk Order Anti-Thioredoxin Antibody

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