SynCAM4 cell adhesion molecule, Immunoglobulin Superfamily, Member 4C (IGSF4C), or Nectin-Like Protein 4 (NECL4) is encoded by the gene CADM4 and is a member of the Immunoglobulin-like Cell Adhesion Molecules family. SynCam4 is a cell adhesion molecule involved in many cell processes including the mediation of cell-cell adhesion and assembly, neuronal migration axon growth and differentiation. SynCAM1 is expressed in several tissue types including brain, kidney and liver. Diseases associated with with this gene include Small Intestine Adenocarcinoma.
Purified by Protein A chromatography
Cadm4 Igsf4c Necl4 Tsll2
Fusion protein amino acids 1-321 (signal peptide and extracellular N-terminus) of mouse SynCAM4 (accession number Q8R464) produced recombinantly in E. Coli
Human, Mouse, Rat
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL650 Ex: 655 nm, Em: 676 nm
Does not cross-react with other SynCAMs (based on KO validation results)
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
12 months from date of receipt
Shipped on ice packs
Cell adhesion molecule 4 (Immunoglobulin superfamily member 4C) (IgSF4C) (Nectin-like protein 4) (NECL-4) (TSLC1-like protein 2)