Anti-Synaptotagmin-6 Antibody FL490 Conjugate (N270/47)

Name: Anti-Synaptotagmin-6 Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-271-FL490
Price: 486.0 USD
Availability: InStock

Our mouse Synaptotagmin-6 FL490 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N270/47. It detects human, mouse, and rat Synaptotagmin-6 and is purified by Protein A chromatography. Works in ICC.

Anti-Synaptotagmin-6 Antibody FL490 Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ICC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-271-FL490

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Synaptotagmin-6

Scientific Background

Synaptotagmins are a family of calcium sensing, membrane trafficking proteins. 17 different synaptotagmins have been identified in mammals. Synaptotagmin 6 is thought to be a key component of the secretory machinery involved in acrosomal exocytosis (Michaut M. et al., 2001).

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N270/47

Isotype

IgG1

Applications

ICC

Host Species

Mouse

Gene Name

Syt6

Molecular Weight

55 kDa

Immunogen

Fusion protein amino acids 246-333 (cytoplasmic C2A domain) of mouse Synaptotagmin-6 (accession number Q9R0N8) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939972

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not cross-react with other Synaptotagmins

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

3110037A08Rik; Synaptotagmin-6; sytVI; Synaptotagmin VI

UniProt ID

Q9R0N8
UniProt Summary: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. May mediate Ca(2+)-regulation of exocytosis in acrosomal reaction in sperm.

NCBI Gene ID

54524

Shipping

Shipped on ice packs

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Anti-Synaptotagmin-6 Antibody FL490 Conjugate (N270/47)

SKU: 75-271-FL490

Product Details

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