Synaptotagmins are a family of calcium sensing, membrane trafficking proteins. 17 different synaptotagmins have been identified in mammals. Synaptotagmin 6 is thought to be a key component of the secretory machinery involved in acrosomal exocytosis (Michaut M. et al., 2001).
Fusion protein amino acids 246-333 (cytoplasmic C2A domain) of mouse Synaptotagmin-6 (also known as Syt6, Synaptotagmin VI and SytVI, accession number Q9R0N8)
Human: 100% identity (88/88 amino acids identical)
Rat: 100% identity (88/88 amino acids identical)
Greater than 70% identity with Synaptotagmin-10, Synaptotagmin-3 and Synaptotagmin-9
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Does not cross-react with other Synaptotagmins
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.