Bulk Order Anti-Synaptotagmin-10 Antibody FL490 Conjugate
Synaptotagmins are a family of calcium sensing, membrane trafficking proteins. 17 different synaptotagmins have been identified in mammals. Synaptotagmin 10 has been shown to function as the Ca2+-sensor that triggers IGF-1 exocytosis in olfactory bulb neurons (Cao P. et al., 2011).
Purified by Protein A chromatography
Fusion protein amino acids 248-335 (cytoplasmic C2A domain) of mouse Synaptotagmin-10 (accession number Q9R0N4) produced recombinantly in E. Coli
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL490 Ex: 491 nm, Em: 515 nm
Does not cross-react with Synaptotagmin-6 or Synaptotagmin-3
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.