Anti-SUR1 Antibody FL650 Conjugate (N289/16)

Name: Anti-SUR1 Antibody FL650 Conjugate
Brand: NeuroMab
SKU: 75-267-FL650
Price: 445.0 USD
Availability: InStock

from NeuroMab

KO Validated

Available Conjugates

Unconjugated

490

550

594

Product Type

Primary Antibody

Species Reactivity

Hamster, Mouse, Rat

Clone

N289/16

Applications

ICC, IHC

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

Abcc8 Sur Sur1

Molecular Weight

180 kDa

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Volume: 200 µL

Variant

Price:

$445

Quantity:

Bulk Order Anti-SUR1 Antibody FL650 Conjugate

Product Details

Target

SUR1

Target Description

Sulfonylurea receptor 1 (SUR1), or ATP binding cassette transporter subfamily C member 8 is encoded by the gene ABCC8 and is a member of the ABC transporter super family. SUR1 acts to modulate ATP sensitive potassium channels and combines with Kir6.2 (KCNJ11). SUR1 is involved in insulin release. SUR1 has broad expression in many tissues including brain, heart, pancreas (beta cells). Diseases associated with this gene include Familial Hyperinsulinemic Hypoglycemia and Diabetes Mellitus.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N289/16

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Abcc8 Sur Sur1

Molecular Weight

180 kDa

Antigen

Fusion protein amino acids 1548-1582 (LVMVLKRGAILEFDKPEKLLSQKDSVFASFVRADK, cytoplasmic C-terminus) of rat SUR1 (accession number Q09429) produced recombinantly in E. Coli

Species Reactivity

Hamster, Mouse, Rat

Antibody Registry ID

AB_2939963

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

Specificity

Does not cross-react with SUR2B (based on KO validation results)

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

ATP-binding cassette sub-family C member 8 (Sulfonylurea receptor 1)

UniProt Details

UniProt (Human): Q09428
UniProt (Immunogen Species): Q09429

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Anti-SUR1 Antibody FL650 Conjugate (N289/16)

Available Conjugates

Anti-SUR1 Antibody FL650 Conjugate
SKU: 75-267-FL650

Bulk Order Anti-SUR1 Antibody FL650 Conjugate

Product Details

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Anti-SUR1 Antibody FL650 Conjugate (N289/16)

Available Conjugates

Anti-SUR1 Antibody FL650 Conjugate SKU: 75-267-FL650

Bulk Order Anti-SUR1 Antibody FL650 Conjugate

Product Details

Anti-SUR1 Antibody FL650 Conjugate
SKU: 75-267-FL650