Anti-SK2 potassium channel Antibody Biotin Conjugate (K78/29)

Name: Anti-SK2 potassium channel Antibody Biotin Conjugate
Brand: NeuroMab
SKU: 75-403-BTN
Price: 543.0 USD
Availability: InStock

Our mouse SK2 potassium channel biotin conjugate monoclonal antibody from NeuroMab is produced in-house from clone K78/29. It detects human, mouse, and rat SK2 potassium channel and is purified by Protein A chromatography. Works in ELISA, IHC, ICC, WB.

Anti-SK2 potassium channel Antibody Biotin Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Carrier-Free

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Data Sheet

SKU: 75-403-BTN

Volume: 200 µL

Variant

Price:

$543.00

Quantity:

Ships: 1-5 business days

Product Details

Target

SK2 potassium channel

Scientific Background

Potassium calcium-activated channel subfamily N member 2 is encoded by the gene KCNN2. KCNN2 is a member of the potassium KCNN family, KCa2.2/KCNN2 subfamily. KCNN2 is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Activation of KCNN2 leads to membrane hyperpolarization. KCNN2 is expressed in the brain. Diseases associated with KCNN2 include Dyskeratosis Congenita, Autosomal Dominant 3 and Coronary Aneurysm.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

K78/29

Isotype

IgG1

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

Kcnn2

Molecular Weight

50-80 kDa (and larger due to isoforms and dimerization/aggregation)

Immunogen

Synthetic peptide amino acids 546-562 (ENYDKHVTYNAERSRSS, cytoplasmic C-terminus) of rat SK2 (accession number P70604)

Immunogen Species

Rat

Species Reactivity

Human, Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

Biotin

Specificity

Does not cross-react with other SK channels

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Small conductance calcium-activated potassium channel protein 2 (SK2) (SKCa 2) (SKCa2) (KCa2.2)

UniProt ID

P70604

Shipping

Shipped on ice packs

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Anti-SK2 potassium channel Antibody Biotin Conjugate (K78/29)

SKU: 75-403-BTN

Product Details

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