Rad And Gem-Like GTP-Binding Protein 2 or GTP-binding protein REM 2 is encoded by the gene Rem2 and is a member of the small GTPase superfamily and the Rad/Rem/Rem2/Gem/Kir (RGK) subfamily. REM2 binds GTP and plays roles in diverse processes including modulation of calcium channel currents, (Ref Zheng JQ et al. 2007), mediation of excitatory and inhibitory synapse development (Ref: Paradis et al. 2007). REM2 is expressed in brain and kidney. Diseases associated with this gene include Long Qt Syndrome.
Purified by Protein A chromatography
45 kDa (and larger due to oligomerization)
Fusion protein amino acids 1-341 (full-length) of rat Rem2 (accession number Q9WTY2)
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL490 Ex: 491 nm, Em: 515 nm
Does not cross-react with Rad, Gem or Rem1
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
12 months from date of receipt
Shipped on ice packs
GTP-binding protein REM 2 (Rad and Gem-like GTP-binding protein 2)