Anti-Rem2 Antibody (N324/2)

Name: Anti-Rem2 Antibody
Brand: NeuroMab
SKU: 75-286
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N324/2

Applications

ICC, IHC, WB

Host Species

Mouse

Format

Purified

Gene Name

Rem2

Molecular Weight

45 kDa (and larger due to oligomerization)

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Adult rat brain immunohistochemistry (with antigen retrieval via sodium citrate pretreatment).

Transfected cell immunoblot: extracts of COS cells transiently transfected with HA-tagged Rem2, Rem, Flag-tagged Rad or untagged Gem or Kv2.1 plasmid and probed with N324/2 (left) or 12CA5 (right) TC supe.

Adult rat brain immunohistochemistry (with antigen retrieval via sodium citrate pretreatment).

Volume: 100 µL

Variant

Price:

$308

Quantity:

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Product Details

Target

GTP-binding protein REM 2 (Rad and Gem-like GTP-binding protein 2)

Target Description

Rad And Gem-Like GTP-Binding Protein 2 or GTP-binding protein REM 2 is encoded by the gene Rem2 and is a member of the small GTPase superfamily and the Rad/Rem/Rem2/Gem/Kir (RGK) subfamily. REM2 binds GTP and plays roles in diverse processes including modulation of calcium channel currents, (Ref Zheng JQ et al. 2007), mediation of excitatory and inhibitory synapse development (Ref: Paradis et al. 2007). REM2 is expressed in brain and kidney. Diseases associated with this gene include Long Qt Syndrome.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N324/2

Isotype

IgG1

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Rem2

Molecular Weight

45 kDa (and larger due to oligomerization)

Antigen

Fusion protein amino acids 1-341 (full-length) of rat Rem2 (also known as Rad and Gem-like-GTP-binding protein 2, accession number Q9WTY2) Mouse: 97% identity (332/341 amino acids identical) Human: 92% identity (315/341 amino acids identical) Less than 50% identity with Rad, Gem and Rem1

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_11001585

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Does not cross-react with Rad, Gem or Rem1

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

GTP-binding protein REM 2 (Rad and Gem-like GTP-binding protein 2)

UniProt Details

UniProt (Human): Q8IYK8
UniProt (Immunogen Species): Q9WTY2

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Anti-Rem2 Antibody (N324/2)

Anti-Rem2 Antibody
SKU: 75-286

Bulk Order Anti-Rem2 Antibody

Product Details

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Anti-Rem2 Antibody (N324/2)

Anti-Rem2 Antibody SKU: 75-286

Bulk Order Anti-Rem2 Antibody

Product Details

Anti-Rem2 Antibody
SKU: 75-286