Adult rat brain immunohistochemistry (with antigen retrieval via sodium citrate pretreatment).
Bulk Order Anti-Rem2 Antibody
GTP-binding protein REM 2 (Rad and Gem-like GTP-binding protein 2)
Rad And Gem-Like GTP-Binding Protein 2 or GTP-binding protein REM 2 is encoded by the gene Rem2 and is a member of the small GTPase superfamily and the Rad/Rem/Rem2/Gem/Kir (RGK) subfamily. REM2 binds GTP and plays roles in diverse processes including modulation of calcium channel currents, (Ref Zheng JQ et al. 2007), mediation of excitatory and inhibitory synapse development (Ref: Paradis et al. 2007). REM2 is expressed in brain and kidney. Diseases associated with this gene include Long Qt Syndrome.
ICC, IHC, WB
45 kDa (and larger due to oligomerization)
Fusion protein amino acids 1-341 (full-length) of rat Rem2 (also known as Rad and Gem-like-GTP-binding protein 2, accession number Q9WTY2)
Mouse: 97% identity (332/341 amino acids identical)
Human: 92% identity (315/341 amino acids identical)
Less than 50% identity with Rad, Gem and Rem1
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.