Anti-PEX6 Antibody FL550 Conjugate (N233/8)

Name: Anti-PEX6 Antibody FL550 Conjugate
Brand: NeuroMab
SKU: 75-285-FL550
Price: 486.0 USD
Availability: InStock

Our mouse PEX6 FL550 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N233/8. It detects human and rat PEX6 and is purified by Protein A chromatography. Works in ICC.

Anti-PEX6 Antibody FL550 Conjugate

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Species Reactivity

Human, Rat

Applications

ICC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-285-FL550

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

PEX6

Scientific Background

Peroxisomal Biogenesis Factor 6 is encoded by the gene PEX6. PEX6 is a member of the AAA ATPase family. PEX6 is a predominantly cytoplasmic protein, which plays a direct role in peroxisomal protein import and is required for PTS1 receptor activity. PEX6 is expressed in the retina. Diseases associated with PEX6 include Peroxisome Biogenesis Disorder 4A and Heimler Syndrome 2.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N233/8

Isotype

IgG1

Applications

ICC

Host Species

Mouse

Gene Name

PEX6 PXAAA1

Molecular Weight

100 kDa

Immunogen

Fusion protein amino acids 2-294 (N-terminus) of human PEX6 (accession number Q8BR86-3) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human, Rat

Antibody Registry ID

AB_2940017

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

HMLR2; Peroxisome assembly factor 2; PAF2; PAF-2; PBD4A; Peroxin-6; PDB4B; Peroxisomal biogenesis factor 6; PXAAA1; Peroxisomal-type ATPase 1; peroxisome biogenesis factor 6; peroxisomal AAA-type ATPase 1

UniProt ID

Q13608
UniProt Summary: Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling. Specifically recognizes PEX5 monoubiquitinated at 'Cys-11', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel. Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5.

NCBI Gene ID

5190

Shipping

Shipped on ice packs

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Anti-PEX6 Antibody FL550 Conjugate (N233/8)

SKU: 75-285-FL550

Product Details

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