Bulk Order Anti-OCRL/INPP5b Antibody FL650 Conjugate
Inositol polyphosphate 5-phosphatase B is encoded by the gene INPP5B. INPP5B is a member of the inositol 1,4,5-triphosphate 5-phosphatase family. INPP5B functions in the regulation of calcium signaling by inactivating inositol phosphates. INPP5B is expressed highest in the urinary bladder. Diseases associated with INPP5B include dent disease 2, lowe oculocerebrorenal syndrome, charcot-marie-tooth disease type 4j, dent disease 1, and frontotemporal dementia and/or amyotrophic lateral sclerosis 2.
Purified by Protein A chromatography
Fusion protein amino acids 1-901 (full-length) of human OCRL (accession number Q01968) produced recombinantly in E. Coli
Human, Mouse, Rat
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL650 Ex: 655 nm, Em: 676 nm
Cross-reacts with INPP5b
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
12 months from date of receipt
Shipped on ice packs
Type II inositol 1,4,5-trisphosphate 5-phosphatase (EC 220.127.116.11) (75 kDa inositol polyphosphate-5-phosphatase) (Phosphoinositide 5-phosphatase) (5PTase)