Anti-Navbeta4 Na+ Channel Antibody FL490 Conjugate (N168/6)

Name: Anti-Navbeta4 Na+ Channel Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-198-FL490
Price: 445.0 USD
Availability: InStock

from NeuroMab Datasheet

Available Conjugates

Unconjugated

550

594

650

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N168/6

Applications

ICC, IHC

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

Scn4b

Molecular Weight

25 kDa

Go to Full Product Details

Volume: 200 µL

Variant

Price:

$445

Quantity:

Bulk Order Anti-Navbeta4 Na+ Channel Antibody FL490 Conjugate

Product Details

Target

Navbeta4 Na+ channel

Target Description

Sodium channel subunit beta-4 or Navbeta4 Na+ channel is encoded by SCN4B. Voltage gated sodium channels are made up of an alpha (pore forming) subunit and 1 or 2 beta subunits. Navß4 is a transmembrane protein and acts as a regulatory subunit in excitable membranes and modulates the kinetics of channel. Nabß4 is expressed in many tissues, including the brain (dorsal root ganglia), spinal cord, heart, and skeletal muscle. Defects in this gene are a cause of long QT syndrome type 10 and Familial Atrial Fibrillation.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N168/6

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Scn4b

Molecular Weight

25 kDa

Antigen

Fusion protein amino acids 184-228 (cytoplasmic C-terminus) of rat Navbeta4 (accession number Q7M730) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2939732

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Sodium channel subunit beta-4

UniProt Details

UniProt (Human): Q8IWT1
UniProt (Immunogen Species): Q7M730

Recover password

Create my account

Anti-Navbeta4 Na+ Channel Antibody FL490 Conjugate (N168/6)

Available Conjugates

Anti-Navbeta4 Na+ Channel Antibody FL490 Conjugate
SKU: 75-198-FL490

Bulk Order Anti-Navbeta4 Na+ Channel Antibody FL490 Conjugate

Product Details

Related Products

Recently Viewed

Anti-Navbeta4 Na+ Channel Antibody FL490 Conjugate (N168/6)

Available Conjugates

Anti-Navbeta4 Na+ Channel Antibody FL490 Conjugate SKU: 75-198-FL490

Bulk Order Anti-Navbeta4 Na+ Channel Antibody FL490 Conjugate

Product Details

Anti-Navbeta4 Na+ Channel Antibody FL490 Conjugate
SKU: 75-198-FL490