Anti-NALCN Antibody FL650 Conjugate (N185/7)

Name: Anti-NALCN Antibody FL650 Conjugate
Brand: NeuroMab
SKU: 75-220-FL650
Price: 460.0 USD
Availability: InStock

Our Anti-NALCN mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N185/7. It detects mouse and rat NALCN, and is purified by Protein A chromatography. It is great for use in ICC.

Species Reactivity

Mouse, Rat

Applications

ICC

Host Species

Mouse

Available Conjugates

Unconjugated

490

550

594

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Data Sheet

SKU: 75-220-FL650

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

NALCN

Target Description

Sodium Leak Channel, Non-Selective is encoded by the gene NALCN. NALCN is a member of the cation-nonselective channel family. NALCN is a voltage-independent, cation-nonselective channel which is permeable to sodium, potassium, and calcium ions. NALCN regulates the resting membrane potential and controls neuronal excitability. NALCN is expressed in the brain, heart, and pancreas. Diseases associated with NALCN include Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay and Hypotonia, Infantile, with Psychomotor Retardation and Characteristic Facies 1.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N185/7

Isotype

IgG1

Applications

ICC

Host Species

Mouse

Gene Name

Nalcn Nca Rb21 Vgcnl1

Molecular Weight

200 kDa

Antigen

Fusion protein amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN (accession number Q6Q760) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2939811

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Sodium leak channel non-selective protein (Four domain-type voltage-gated ion channel alpha-1 subunit) (Rb21-channel) (Voltage gated channel-like protein 1)

UniProt Details

UniProt (Human): Q8IZF0
UniProt (Immunogen Species): Q6Q760

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Anti-NALCN Antibody FL650 Conjugate (N185/7)

SKU: 75-220-FL650

Product Details

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