Anti-MMACHC Antibody FL490 Conjugate (N230/21)

Name: Anti-MMACHC Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-239-FL490
Price: 460.0 USD
Availability: InStock

Our Anti-MMACHC mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N230/21. It detects human and mouse MMACHC, and is purified by Protein A chromatography. It is great for use in ICC.

Species Reactivity

Human, Mouse

Applications

ICC

Host Species

Mouse

Available Conjugates

Unconjugated

550

594

650

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Data Sheet

SKU: 75-239-FL490

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

MMACHC

Target Description

Metabolism of Cobalamin Associated C is encoded by the gene MMACHC. MMACHC is a member of the MMACHC family. MMACHC may have a role in the binding and intracellular trafficking of of cobalamin. MMACHC is widely expressed with higher levels in the liver, spleen, lymph nodes, thymus, and bone marrow. Diseases associated with MMACHC include Methylmalonic Aciduria and Homocystinuria, Cblc Type and Methylmalonic Acidemia with Homocystinuria.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N230/21

Isotype

IgG1

Applications

ICC

Host Species

Mouse

Gene Name

MMACHC

Molecular Weight

32 kDa

Antigen

Fusion protein amino acids 1-282 (full-length) of human MMACHC (accession number Q9Y4U1) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse

Antibody Registry ID

AB_2939868

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Methylmalonic aciduria and homocystinuria type C protein (EC 1.16.1.-) (CblC) (Cyanocobalamin reductase (cyanide-eliminating))

UniProt Details

UniProt (Human): Q9Y4U1
UniProt (Immunogen Species): Q9Y4U1

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Anti-MMACHC Antibody FL490 Conjugate (N230/21)

SKU: 75-239-FL490

Product Details

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