Bulk Order Anti-MiRP4 K+ Channel Antibody FL650 Conjugate
Potassium voltage-gated channel subfamily E regulatory subunit 5 is encoded by the gene KCNE5. KCNE5 is a member of the potassium channel KCNE family. KCNE5 is a potassium channel ancillary subunit that is essential for generation of some native K(+) currents by forming a heteromeric ion channel complex with voltage-gated potassium (Kv) channel pore-forming alpha subunits. KCNE5 functions as an inhibitory beta-subunit of the repolarizing cardiac potassium ion channel KCNQ1. KCNE5 is expressed in the heart, skeletal muscle, brain, spinal cord, and placenta. Diseases associated with KCNE5 include brugada syndrome and alport syndrome-intellectual disability-midface hypoplasia-elliptocytosis syndrome.
Purified by Protein A chromatography
KCNE5 AMMECR2 KCNE1L RCG23148
Fusion protein amino acids 1-60 (extracellular N-terminus) and 82-142 (cytoplasmic C-terminus) of human MiRP4 (accession number Q9UJ90) produced recombinantly in E. Coli
Human, Mouse, Rat
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL650 Ex: 655 nm, Em: 676 nm
No cross-reactivity reported
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.