Anti-MiRP4 K+ Channel Antibody (N472/88)

Name: Anti-MiRP4 K+ Channel Antibody
Brand: NeuroMab
SKU: 75-469
Price: 319.0 USD
Availability: InStock

Our Anti-MiRP4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N472/88. It detects human, mouse, and rat MiRP4, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-469

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

MiRP4

Target Description

Potassium voltage-gated channel subfamily E regulatory subunit 5 is encoded by the gene KCNE5. KCNE5 is a member of the potassium channel KCNE family. KCNE5 is a potassium channel ancillary subunit that is essential for generation of some native K(+) currents by forming a heteromeric ion channel complex with voltage-gated potassium (Kv) channel pore-forming alpha subunits. KCNE5 functions as an inhibitory beta-subunit of the repolarizing cardiac potassium ion channel KCNQ1. KCNE5 is expressed in the heart, skeletal muscle, brain, spinal cord, and placenta. Diseases associated with KCNE5 include brugada syndrome and alport syndrome-intellectual disability-midface hypoplasia-elliptocytosis syndrome.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N472/88

Isotype

IgG2a

Applications

ICC, WB

Host Species

Mouse

Gene Name

KCNE5 AMMECR2 KCNE1L RCG23148

Antigen

Fusion protein amino acids 1-60 (extracellular N-terminus) and 82-142 (cytoplasmic C-terminus) of human MiRP4 (accession number Q9UJ90) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2722669

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

MiRP4 (Potassium channel subunit beta MiRP4) (Potassium voltagegatedchannel subfamily E regulatory beta subunit 5) (Voltage-gated potassium channelaccessory subunit 5) (AMME syndrome candidate gene 2 protein) (Potassium voltage-gatedchannel subfamily E member 1-like protein) (MinK-like protein)

UniProt Details

UniProt (Human): Q9UJ90
UniProt (Immunogen Species): Q9UJ90

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Anti-MiRP4 K+ Channel Antibody (N472/88)

SKU: 75-469

Product Details

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