Potassium voltage-gated channel subfamily E regulatory subunit 5 is encoded by the gene KCNE5. KCNE5 is a member of the potassium channel KCNE family. KCNE5 is a potassium channel ancillary subunit that is essential for generation of some native K(+) currents by forming a heteromeric ion channel complex with voltage-gated potassium (Kv) channel pore-forming alpha subunits. KCNE5 functions as an inhibitory beta-subunit of the repolarizing cardiac potassium ion channel KCNQ1. KCNE5 is expressed in the heart, skeletal muscle, brain, spinal cord, and placenta. Diseases associated with KCNE5 include brugada syndrome and alport syndrome-intellectual disability-midface hypoplasia-elliptocytosis syndrome.
Purified
1 mg/mL
Monoclonal
N472/88
IgG2a
ICC, WB
Mouse
KCNE5
AMMECR2 KCNE1L RCG23148
Fusion protein amino acids 1-60 (extracellular N-terminus) and 82-142 (cytoplasmic C-terminus) of human MiRP4 (also known as Potassium channel subunit beta MiRP4, Potassium voltagegated channel subfamily E regulatory beta subunit 5, Voltage-gated potassium channel accessory subunit 5, AMME syndrome candidate gene 2 protein, Potassium voltage-gated channel subfamily E member 1-like protein, MinK-like protein, KCNE5, KCNE1L, AMMECR2 and RCG23148, accession number Q9UJ90)
Human, Mouse, Rat
AB_2722669
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
