Anti-Kv4.2 Potassium Channel Antibody FL650 Conjugate (L28/4)

Name: Anti-Kv4.2 Potassium Channel Antibody FL650 Conjugate
Brand: NeuroMab
SKU: 75-361-FL650
Price: 445.0 USD
Availability: InStock

from NeuroMab Datasheet

KO Validated

Available Conjugates

Unconjugated

490

550

594

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

L28/4

Applications

ICC, IHC

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

Kcnd2

Molecular Weight

70 kDa

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Volume: 200 µL

Variant

Price:

$445

Quantity:

Bulk Order Anti-Kv4.2 Potassium Channel Antibody FL650 Conjugate

Product Details

Target

Kv4.2 potassium channel

Target Description

Potassium voltage-gated channel subfamily D member 2 or Kv4.2 potassium channel subunit is encoded by the gene KCND2. Kv4.2 is an alpha subunit of the voltage-gated potassium channel (Shal) family and mediates transmembrane potassium transport in excitable membranes. Kv4.2 is an integral membrane protein that combines to form tetramers. Kv4.2 is detected in the heart and brain. In brain it is found at the cell junction, synapse, postsynaptic cell membrane. Diseases associated with this gene include Cycloplegia and early myoclonic encephalopathy.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

L28/4

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Kcnd2

Molecular Weight

70 kDa

Antigen

Fusion protein amino acids 471-630 (cytoplasmic C-terminus) of rat Kv4.2 (accession number Q63881) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2940211

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

Specificity

Does not cross-react with Kv4.3 (based on KO validation results)

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Potassium voltage-gated channel subfamily D member 2 (RK5) (Shal1) (Voltage-gated potassium channel subunit Kv4.2)

UniProt Details

UniProt (Human): Q9NZV8
UniProt (Immunogen Species): Q63881

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Anti-Kv4.2 Potassium Channel Antibody FL650 Conjugate (L28/4)

Available Conjugates

Anti-Kv4.2 Potassium Channel Antibody FL650 Conjugate
SKU: 75-361-FL650

Bulk Order Anti-Kv4.2 Potassium Channel Antibody FL650 Conjugate

Product Details

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Anti-Kv4.2 Potassium Channel Antibody FL650 Conjugate (L28/4)

Available Conjugates

Anti-Kv4.2 Potassium Channel Antibody FL650 Conjugate SKU: 75-361-FL650

Bulk Order Anti-Kv4.2 Potassium Channel Antibody FL650 Conjugate

Product Details

Anti-Kv4.2 Potassium Channel Antibody FL650 Conjugate
SKU: 75-361-FL650