Anti-Kv11.3 Potassium Channel Antibody (N447/24)

Name: Anti-Kv11.3 Potassium Channel Antibody
Brand: NeuroMab
SKU: 75-440
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

N447/24

Applications

ICC, IHC, WB

Host Species

Mouse

Format

Purified

Gene Name

Kcnh7 Erg3

Molecular Weight

120 kDa

Go to Full Product Details

Adult rat brain membrane immunoblot.

Volume: 100 µL

Variant

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$308

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Product Details

Target

Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3) (ERG-3) (Eag-related protein 3) (Ether-a-go-go-related protein 3) (Voltage-gated potassium channel subunit Kv11.3)

Target Description

ERG3 (ether-a-go-go–related gene 3), Potassium voltage-gated channel subfamily H member 7, or Kv11.3 potassium channel is encoded by the gene Kcnh7 and is a member of the ERG family of voltage activated potassium channels. Kv11.3 is a pore forming, alpha subunit of the potassium channel. Erg channels play roles in regulating the resting membrane potential and action potential duration. Kv11.3 is detected in total brain, in superior cervical, mesenteric and celiac ganglia, and at very low levels in retina and is also found in pituitary.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N447/24

Isotype

IgG2b

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Kcnh7 Erg3

Molecular Weight

120 kDa

Antigen

Fusion protein amino acids 894-1059 (cytoplasmic C-terminus) of rat Kv11.3 (also known as Voltage-gated potassium channel subunit Kv11.3, Ether-a-go-go-related gene potassium channel 3, Ether-a-go-go-related protein 3, Eag-related protein 3, Potassium voltage-gated channel subfamily H member 7, Erg3 and Kcnh7, accession number O54852); Mouse: 93% identity (155/166 amino acids identical); Human: 79% identity (131/166 amino acids identical); 50% identity with Kv11.1 and Kv11.2

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2576199

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

UniProt Details

UniProt (Human): Q9NS40
UniProt (Immunogen Species): O54852

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Anti-Kv11.3 Potassium Channel Antibody (N447/24)

Anti-Kv11.3 Potassium Channel Antibody
SKU: 75-440

Bulk Order Anti-Kv11.3 Potassium Channel Antibody

Product Details

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Anti-Kv11.3 Potassium Channel Antibody (N447/24)

Anti-Kv11.3 Potassium Channel Antibody SKU: 75-440

Bulk Order Anti-Kv11.3 Potassium Channel Antibody

Product Details

Anti-Kv11.3 Potassium Channel Antibody
SKU: 75-440