Anti-Kir2.1 K+ Channel Antibody FL550 Conjugate (N112B/14)
Our Anti-Kir2.1 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N112B/14. It detects mouse and rat Kir2.1 K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
SKU: 75-210-FL550
Product Details
Kir2.1 K+ channel
Kir2.1 (KCNJ2) is a member of the inward rectifier potassium ion channel family which also includes Kir2.2 and Kir2.3. Kir2.1 is expressed in the membranes of many tissues, including heart, skeletal muscle, kidney and diffusely distributed throughout the brain. Kir2.1 has a role in cardiac excitability and has been shown to have interactions with CLG4, Interleukin 16 and TRAK2. Defects in Kir2.1 are involved with the diseases long QT syndrome type 7 (also known as andersen-Tawil syndrome), short QT syndrome 3, and Familial Atrial Fibrillation 9.
Purified by Protein A chromatography
0.5 mg/mL
Monoclonal
N112B/14
IgG1
ICC, IHC
Mouse
Kcnj2 Irk1
55 kDa
Synthetic peptide amino acids 390-411 (cytoplasmic C-terminus) of mouse Kir2.1 (accession number P35561)
Human, Mouse, Rat
AB_2939777
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL550 Ex: 550 nm, Em: 575 nm
No cross-reactivity against Kir2.2 or Kir2.3
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
12 months from date of receipt
Shipped on ice packs
Inward rectifier potassium channel 2 (Inward rectifier K(+) channel Kir2.1) (IRK-1) (Potassium channel, inwardly rectifying subfamily J member 2)
UniProt (Human): P63252
UniProt (Immunogen Species): P35561
UniProt (Immunogen Species): P35561