Kir2.1 (KCNJ2) is a member of the inward rectifier potassium ion channel family which also includes Kir2.2 and Kir2.3. Kir2.1 is expressed in the membranes of many tissues, including heart, skeletal muscle, kidney and diffusely distributed throughout the brain. Kir2.1 has a role in cardiac excitability and has been shown to have interactions with CLG4, Interleukin 16 and TRAK2. Defects in Kir2.1 are involved with the diseases long QT syndrome type 7 (also known as andersen-Tawil syndrome), short QT syndrome 3, and Familial Atrial Fibrillation 9.
Synthetic peptide amino acids 390-411 (cytoplasmic C-terminus) of mouse Kir2.1 also known as Inward rectifier potassium channel 2 or subfamily J member 2, Kcnj2 and Irk1, accession number P35561); Rat: 100% identity (22/22 amino acids identical); Human: 90% identity (20/22 amino acids identical)
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
No cross-reactivity against Kir2.2 or Kir2.3
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.