Anti-KCC2 Antibody FL550 Conjugate (N1/66)

Name: Anti-KCC2 Antibody FL550 Conjugate
Brand: NeuroMab
SKU: 75-050-FL550
Price: 445.0 USD
Availability: InStock

from NeuroMab

Available Conjugates

Unconjugated

490

594

650

Product Type

Primary Antibody

Species Reactivity

Chicken, Human, Mouse, Rat

Clone

N1/66

Applications

ICC, IHC

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

Slc12a5 Kcc2 Kiaa1176

Molecular Weight

140 kDa

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Volume: 200 µL

Variant

Price:

$445

Quantity:

Bulk Order Anti-KCC2 Antibody FL550 Conjugate

Product Details

Target

KCC2

Target Description

Solute carrier family 12 member 5 is encoded by the gene SLC12A5 and belongs to the SLC12 family of cation-coupled chloride transporters. SLC12A5 is an integral membrane K-Cl cotransporter that mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis. Diseases associated with SLC12A5 include Early Infantile Epileptic Encephalopathy 34 and Idiopathic Generalized Epilepsy 14.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N1/66

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Slc12a5 Kcc2 Kiaa1176

Molecular Weight

140 kDa

Antigen

Fusion protein amino acids 932-1043 (intracellular carboxyl terminus) of rat KCC2b (accession number Q63633) produced recombinantly in E. Coli

Species Reactivity

Chicken, Human, Mouse, Rat

Antibody Registry ID

AB_2939221

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

Does not react with KCC1, KCC3 or KCC4

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Solute carrier family 12 member 5 (Electroneutral potassium-chloride cotransporter 2) (K-Cl cotransporter 2) (mKCC2) (Neuronal K-Cl cotransporter)

UniProt Details

UniProt (Human): Q9H2X9
UniProt (Immunogen Species): Q63633

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Anti-KCC2 Antibody FL550 Conjugate (N1/66)

Available Conjugates

Anti-KCC2 Antibody FL550 Conjugate
SKU: 75-050-FL550

Bulk Order Anti-KCC2 Antibody FL550 Conjugate

Product Details

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Anti-KCC2 Antibody FL550 Conjugate (N1/66)

Available Conjugates

Anti-KCC2 Antibody FL550 Conjugate SKU: 75-050-FL550

Bulk Order Anti-KCC2 Antibody FL550 Conjugate

Product Details

Anti-KCC2 Antibody FL550 Conjugate
SKU: 75-050-FL550