Anti-IP3 Receptor, Type 1 Antibody (BSA and Azide free) (L24/18)

Name: Anti-IP3 Receptor, Type 1 Antibody (BSA and Azide free)
Brand: NeuroMab
SKU: 75-035-CF
Price: 486.0 USD
Availability: InStock

Our mouse IP3 receptor, type 1 carrier-free monoclonal antibody from NeuroMab is produced in-house from clone L24/18. It detects human, mouse, and rat IP3 receptor, type 1 and is purified by Protein A chromatography. Works in WB, IHC, ICC, ELISA.

Anti-IP3 Receptor, Type 1 Antibody (BSA and Azide free)

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Biotin

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Data Sheet

SKU: 75-035-CF

Volume: 100 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

IP3 receptor, type 1

Scientific Background

Inositol 1,4,5-trisphosphate receptor type 1 or IP3 receptor type 1 (IP3R1) serves as a receptor for IP3. It is expressed in many tissues in the endoplasmic reticulum to facilitate calcium release from the ER. In brain, (IP3R1) is predominantly expressed in cerebellar Purkinje neurons.. Mutations in this gene cause spinocerebellar ataxia type 15 and spinocerebellar Ataxia 29.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.6-1.0 mg/mL

Clonality

Monoclonal

Clone

L24/18

Isotype

IgG1

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

Itpr1 Insp3r

Molecular Weight

300 kDa (varies due to glycosylation)

Immunogen

Fusion protein amino acids 2680-2749 (cytoplasmic carboxyl terminus) of rat type 1 IP3R (accession number P29994) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Human, Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Buffer

PBS

Conjugate

Unconjugated

Specificity

Does not recognize type 2 and type 3 IP3R’s

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP-3-R) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)

UniProt ID

P29994

Shipping

Shipped on ice packs

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Anti-IP3 Receptor, Type 1 Antibody (BSA and Azide free) (L24/18)

SKU: 75-035-CF

Product Details

Bulk Order Anti-IP3 Receptor, Type 1 Antibody (BSA and Azide free)

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