Anti-IP3 Receptor, Type 1 Antibody (L24/18)

Our Anti-IP3 receptor, type 1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L24/18. It detects human, mouse, and rat IP3 receptor, type 1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.



SKU: 75-035

Volume: 100 µL
1-2 business days
Price:
Sale price$319

Product Specific References for Applications and Species

Immunocytochemistry: Mouse
PMID Dilution Publication
37838947not listedHorvath, JD, et al. 2023. α-Synuclein-dependent increases in PIP5K1γ drive inositol signaling to promote neurotoxicity. Cell Reports, 113244.
293211371:200Kong, J.N., et al. 2018. Novel function of ceramide for regulation of mitochondrial ATP release in astrocytes. Journal of Lipid Research, 488-506.
25270259not listedFos, C., et al. 2014. Association of the EF-hand and PH domains of the guanine nucleotide exchange factor SLAT with IP₃ receptor 1 promotes Ca²⁺ signaling in T cells.. Science Signaling, ra93.
Immunocytochemistry: Rat
PMID Dilution Publication
271475591:100Wang, Q., et al. 2016. Local coupling of TRPC6 to ANO1/TMEM16A channels in smooth muscle cells amplifies vasoconstriction in cerebral arteries. American Journal of Physiology-Cell Physiology, C1001-C1009.
236700891:100Seo, J.W., et al. 2013. Proteomic analysis of primary cultured rat cortical neurons in chemical ischemia.. Neurochemical Research, 1648-1660.
207135461:100Zhao, G., et al. 2010. Type 1 IP3 receptors activate BKCa channels via local molecular coupling in arterial smooth muscle cells.. The Journal of General Physiology, 283-291.
187996501:100Zhao, G., et al. 2008. Type 1 inositol 1,4,5-trisphosphate receptors mediate UTP-induced cation currents, Ca2+ signals, and vasoconstriction in cerebral arteries.. American Journal of Physiology-Cell Physiology, C1376-C1384.
Immunohistochemistry: Human
PMID Dilution Publication
353283811:50Foulon, A., et al. 2022. Inositol (1,4,5)-Trisphosphate Receptors in Invasive Breast Cancer: A New Prognostic Tool?. International journal of molecular sciences, 2962.
Immunohistochemistry: Mouse
PMID Dilution Publication
271623681:200Spassieva, S.D., et al. 2016. Ectopic expression of ceramide synthase 2 in neurons suppresses neurodegeneration induced by ceramide synthase 1 deficiency. PNAS USA, 5928-5933.
223314181:500Westcott, E.B., et al. 2012. Function and expression of ryanodine receptors and inositol 1,4,5-trisphosphate receptors in smooth muscle cells of murine feed arteries and arterioles.. The Journal of Physiology, 1849-1869.
206498391:600Fang, F., et al. 2010. Neurosteroid transport by the organic solute transporter OSTα-OSTβ.. Journal of Neurochemistry, 220-233.
18946029not listedIsakson, B.E., et al. 2008. Localized expression of an Ins(1,4,5)P3 receptor at the myoendothelial junction selectively regulates heterocellular Ca2+ communication.. Journal of Cell Science, 3664-3673.
Immunoprecipitation: Human
PMID Dilution Publication
285069281ugWilson, L.S., et al. 2017. Distinct phosphodiesterase 5A-containing compartments allow selective regulation of cGMP-dependent signalling in human arterial smooth muscle cells. Cell Signalling, 204-211.
18757735not listedWilson, L.S., et al. 2008. Compartmentation and compartment-specific regulation of PDE5 by protein kinase G allows selective cGMP-mediated regulation of platelet functions.. PNAS USA, 13650-13655.
Immunoprecipitation: Mouse
PMID Dilution Publication
29386119not listedChristie, M.J., et al. 2018. Effects of intrauterine growth restriction on Ca2+-activated force and contractile protein expression in the mesenteric artery of 1-year-old Wistar-Kyoto rats. Journal of Physiology and Biochemistry, 111-121.
Immunoprecipitation: Rat
PMID Dilution Publication
20713546not listedZhao, G., et al. 2010. Type 1 IP3 receptors activate BKCa channels via local molecular coupling in arterial smooth muscle cells.. The Journal of General Physiology, 283-291.
Western Blot: Canine
PMID Dilution Publication
28381466not listedTadevosyan, A., et al. 2017. Intracellular angiotensin‐II interacts with nuclear angiotensin receptors in cardiac fibroblasts and regulates rna synthesis, cell proliferation, and collagen secretion. . Journal of the American Heart Association, 6(4), p., e004965.
Western Blot: Human
PMID Dilution Publication
353283811:500Foulon, A., et al. 2022. Inositol (1,4,5)-Trisphosphate Receptors in Invasive Breast Cancer: A New Prognostic Tool?. International journal of molecular sciences, 2962.
Western Blot: Mouse
PMID Dilution Publication
32675284not listedArgent, L., et al. 2020. Caspr2 interacts with type 1 inositol 1,4,5-trisphosphate receptor in the developing cerebellum and regulates Purkinje cell morphology. Journal of Biological Chemistry, 12716-12726.
29386119not listedChristie, M.J., et al. 2018. Effects of intrauterine growth restriction on Ca2+-activated force and contractile protein expression in the mesenteric artery of 1-year-old Wistar-Kyoto rats. Journal of Physiology and Biochemistry, 111-121.
242595181:1000Dagley, L.F., et al. 2014. Quantitative proteomic profiling reveals novel region-specific markers in the adult mouse brain.. Proteomics., 241-261.
240979791:1000Abou-Saleh, H., et al. 2013. Inositol 1,4,5-trisphosphate (IP3) receptor up-regulation in hypertension is associated with sensitization of Ca2+ release and vascular smooth muscle contractility.. The Journal of Biological Chemistry, 32941-32951.
19193873not listedTang, T.S., et al. 2009. Neuroprotective effects of inositol 1,4,5-trisphosphate receptor C-terminal fragment in a Huntington''s disease mouse model.. Journal of Neuroscience, 1257-1266.
19036964not listedChen, X., et al. 2008. Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3.. Journal of Neuroscience, 12713-12724.
18946029not listedIsakson, B.E., et al. 2008. Localized expression of an Ins(1,4,5)P3 receptor at the myoendothelial junction selectively regulates heterocellular Ca2+ communication.. Journal of Cell Science, 3664-3673.
Western Blot: Rat
PMID Dilution Publication
247268281:1000Tykocki, N.R., et al. 2015. Divergent signaling mechanisms for venous versus arterial contraction as revealed by endothelin-1.. Journal of Vascular Surgery, 721-733.
23670089not listedSeo, J.W., et al. 2013. Proteomic analysis of primary cultured rat cortical neurons in chemical ischemia.. Neurochemical Research, 1648-1660.
21098487not listedAdebiyi, A., et al. 2011. Caveolin-1 assembles type 1 inositol 1,4,5-trisphosphate receptors and canonical transient receptor potential 3 channels into a functional signaling complex in arterial smooth muscle cells.. The Journal of Biological Chemistry, 4341-4348.
20713546not listedZhao, G., et al. 2010. Type 1 IP3 receptors activate BKCa channels via local molecular coupling in arterial smooth muscle cells.. The Journal of General Physiology, 283-291.
186165581:3 (supe)Ingram, E.A., et al. 2009. Prolonged infusion of inhibitors of calcineurin or L-type calcium channels does not block mossy fiber sprouting in a model of temporal lobe epilepsy.. Epilepsia, 56-64.
Additional Publications: Unspecified
PMID Publication
31927696Christie, M.J., et al. 2020. Effects of intrauterine growth restriction on Ca2+-activated force and contractile protein expression in the mesenteric artery of 1-year-old Wistar-Kyoto rats. Journal of Physiology and Biochemistry, 111-121.

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