Anti-ICK Antibody FL490 Conjugate (N451/73)

Name: Anti-ICK Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-437-FL490
Price: 445.0 USD
Availability: InStock

from NeuroMab Datasheet

Available Conjugates

Unconjugated

550

594

650

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N451/73

Applications

ICC, IHC

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

Ick

Molecular Weight

70 kDa

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Volume: 200 µL

Variant

Price:

$445

Quantity:

Bulk Order Anti-ICK Antibody FL490 Conjugate

Product Details

Target

ICK

Target Description

Serine/threonine-protein kinase ICK is encoded by the gene Ick. Ick is a member of the protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily. Ick has an essential role in ciliogenesis. Ick is envolved in the control of ciliary length by regulating the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips. Ick is highly expressed in the colon and lungs, with lower levels of expression in the heart, esophagus, stomach, small intestine, and ovaries. Diseases associated with Ick include endocrine-cerebroosteodysplasia, juvenile myoclonic epilepsy 10, and juvenile myoclonic epilepsy 1.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N451/73

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Ick

Molecular Weight

70 kDa

Antigen

Fusion protein amino acids 290-629 (C-terminus) of mouse ICK (accession number Q9JKV2) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2940456

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK)

UniProt Details

UniProt (Human): Q9UPZ9
UniProt (Immunogen Species): Q9JKV2

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Anti-ICK Antibody FL490 Conjugate (N451/73)

Available Conjugates

Anti-ICK Antibody FL490 Conjugate
SKU: 75-437-FL490

Bulk Order Anti-ICK Antibody FL490 Conjugate

Product Details

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Anti-ICK Antibody FL490 Conjugate (N451/73)

Available Conjugates

Anti-ICK Antibody FL490 Conjugate SKU: 75-437-FL490

Bulk Order Anti-ICK Antibody FL490 Conjugate

Product Details

Anti-ICK Antibody FL490 Conjugate
SKU: 75-437-FL490